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YM BioSciences Inc.(YMI) AT 1.50
Fundamental: 8
Chart: 7
March 20, 2007
YM BioSciences, Inc., a development stage biopharmaceutical
company, engages in the research and development of products
primarily for the treatment of cancer. Its product candidates
in the clinical stage of development include Tesmilifene,
Nimotuzumab, AeroLEF, and Norelin.
The lead drug Tesmilifene is already halted on Jan
30, 2007. The Data Safety Monitoring Board advised the Company
to stop the trial based on an interim analysis of 351 events,
indicating it is very unlikely significant differences in
overall survival will be shown between treatment arms as the
data mature. The share price dropped more than 50%.
YMI still has two other drugs in the Phase III and Phase
II trial.
Nimotuzumab:
- During the quarter, global development of nimotuzumab in
multipletumor types, including pediatric and adult glioma,
pancreatic cancer, prostate cancer, non-small cell cancer,
esophageal cancer, cervical cancer, and breast cancer, continued
through a consortium of international development partners.
Enrollment should be completed during the first half of 2007
in a pivotal Phase III trial of nimutuzumab as first-line
therapy in pediatric pontine glioma being conducted by\ Oncoscience
AG in Germany. YM BioSciences is in the planning stages of
a Phase II study in the same indication in the United States
and Canada.
AeroLEF(TM):
- Final results from a two-part Phase IIb trial (DLKLEF-AP4)
in post- surgical pain are expected in the first half of 2007.
The second part of this study, still underway, is a randomized,
double-blind, placebo controlled trial of 99 patients designed
to evaluate the safety and efficacy of AeroLEF(TM) for the
management of pain following elective orthopedic surgery.
Results from Part I of the study, an open-label segment, were
presented at the American Society of Anesthesiologists (ASA)
Annual Meeting in October, 2006. These data suggested that
inhaled AeroLEF(TM) was well tolerated and produced clinically
meaningful, highly individualized analgesia for acute post-surgical
pain.
As at December 31, 2006 the Company had cash, cash equivalents
and short-term deposits totaling $86.0 million and accounts
payable and accrued liabilities of $2.1 million compared to
$88.3 million and $3.7 million respectively at June 30, 2006.
It has about $1.35 cash/share and and will have enough cash
to last another 2 years.
YMI already formed a bottom at $1.50 and now forming a base
around $1.50. YMI should trade similar to THLD's pattern,
and the 3 months target is $2.00 and possibly much higher.
Stop loss at $1.38.

Fair Disclosure: Do not hold a long position.
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